Comparison of Orch-OR hypothesis with the TGD point of view

Penrose-Hameroff  (P-H) model and its variants such as Diosi-Penrose (D-P)  model  have been leading candidates for a quantum theory of consciousness. In light of recent experiments and theoretical arguments, the   D-P model  looks highly implausible. The key problem is energy conservation, which is actually the  central problem of general relativity and  caused by  loss of Poincare invariance. The basic idea of Penrose about quantum gravitational superposition is almost a must but in the framework of general relativity its mathematical realization is not possible.

TGD provides an alternative view based on the identification of space-times as 4-surfaces in M⁴× CP₂ related by M⁸-H duality to 4-surfaces in M⁸. In this approach Poincare invariance is exact. In the TGD  framework the  hierarchy of Planck constants h_eff=nh₀ includes also gravitational Planck constant h_gr= GMm/v₀ introduced first by  Nottale. This makes it possible to realize quantum  coherence (in particular, gravitational one ) in arbitrarily long spatial and temporal scales.

In this article P-H and P-P models are compared with the TGD point of view. In TGD, the generation of quantum gravitational binding energy liberates  energy and provides the basic mechanism of metabolism and a direct connection with quantum biochemistry emerges. The gravitational magnetic bodies (MBs) of Earth and Sun are  in an essential role. Could one invent a mechanism involving only self-gravitational interaction energies of the living body itself?  The large gravitational Compton length Λ_gr= GM/v₀ requires the presence of a large mass, say star, which would serve as basic metabolic energy source but the presence of a planet is not necessary in the prebiotic stage.

There are strong indications that water is a quantum critical system at the physiological temperature range. This suggests that scaled variants of magnetic bodies  of water blobs as candidates for proto cells appear in quantum superposition with values of the parameter v₀. This would induce  large density fluctuations at the level of the ordinary biomatter. State function reduction would  induce  a phase transition to a scaled-up state in the presence of energy feed. The return to the original state would liberate the gravitational energy as metabolic  energy.   Note that there are also indications for the quantum (gravitational) criticality of microtubules so that they would be very special from the point of view of life and  neuron level consciousness.   

The gravitational self-interaction energy for water blobs with Planck mass corresponds to an energy scale of  3.5 meV identifiable as the energy difference  between two opposite  membrane potentials. Could gravitational metabolic energy make possible the action potential of proto cells observed even for monocellulars?

See the chapter Quantum gravitation and quantum biology in TGD Universe or article Comparison of Orch-OR hypothesis with the TGD point of view.